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1

A bio-inspired cell-free system for cannabinoid production from inexpensive inputs

Valliere, Meaghan A., Korman, Tyler P., Arbing, Mark A., Bowie, James U.

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 3.36 MB

2020

2

Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization

Crawford, Jason M., Korman, Tyler P., Labonte, Jason W., Vagstad, Anna L., Hill, Eric A., Kamari-Bidkorpeh, Oliver, Tsai, Shiou-Chuan, Townsend, Craig A.

Journal:

Year:

2009

Language:

english

File:

PDF, 782 KB

english, 2009

3

Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution

Tyler P Korman, Bobby Sahachartsiri, David M Charbonneau…

Journal:

Biotechnology for Biofuels

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

4

Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase

Javidpour, Pouya, Korman, Tyler Paz, Shakya, Gaurav, Tsai, Shiou-Chuan

Journal:

Year:

2011

Language:

english

File:

PDF, 4.15 MB

english, 2011

5

A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates

Korman, Tyler P., Sahachartsiri, Bobby, Li, Dan, Vinokur, Jeffrey M., Eisenberg, David, Bowie, James U.

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 367 KB

english, 2014

6

The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase

Javidpour, Pouya, Bruegger, Joel, Srithahan, Supawadee, Korman, Tyler P., Crump, Matthew P., Crosby, John, Burkart, Michael D., Tsai, Shiou-Chuan

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

7

A synthetic biochemistry molecular purge valve module that maintains redox balance

Opgenorth, Paul H., Korman, Tyler P., Bowie, James U.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1000 KB

english, 2014

8

Improving the tolerance of Escherichia coli to medium-chain fatty acid production

Sherkhanov, Saken, Korman, Tyler P., Bowie, James U.

Journal:

Metabolic Engineering

Year:

2014

Language:

english

File:

PDF, 771 KB

english, 2014

9

Inhibition Kinetics and Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase †,‡

Korman, Tyler Paz, Tan, Yu-Hong, Wong, Justin, Luo, Ray, Tsai, Shiou-Chuan

Journal:

Year:

2008

Language:

english

File:

PDF, 608 KB

english, 2008

10

X-ray Crystallographic Structure of an Artificial β-Sheet Dimer

Khakshoor, Omid, Lin, Aaron J., Korman, Tyler P., Sawaya, Michael R., Tsai, Shiou-Chuan, Eisenberg, David, Nowick, James S.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 3.91 MB

english, 2010

11

Structural Analysis of Actinorhodin Polyketide Ketoreductase: Cofactor Binding and Substrate Specificity ‡

Korman, Tyler Paz, Hill, Jason Anthony, Vu, Thanh Nhat, Tsai, Shiou-Chuan

Journal:

Year:

2004

Language:

english

File:

PDF, 1.33 MB

english, 2004

12

Evidence of a Novel Mevalonate Pathway in Archaea

Vinokur, Jeffrey M., Korman, Tyler P., Cao, Zheng, Bowie, James U.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

13

Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases

Vinokur, Jeffrey M., Korman, Tyler P., Sawaya, Michael R., Collazo, Michael, Cascio, Duillio, Bowie, James U.

Journal:

Protein Science

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

14

Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis

Tyler Paz Korman, Jason M. Crawford, Jason W. Labonte, Adam G. Newman, Justin Wong, Craig A. Townsend, Shiou-Chuan Tsai and Stephen J. Benkovic

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

15

Progressive Multifocal Leukoencephalopathy, Efalizumab, and Immunosuppression

Korman, Benjamin D., Tyler, Kenneth L., Korman, Neil J.

Journal:

Archives of Dermatology

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

16

Comprehensive Natural Products II || Structural Enzymology of Polyketide Synthase: The Structure–Sequence–Function Correlation

Korman, Tyler Paz

Year:

2010

Language:

english

File:

PDF, 3.17 MB

english, 2010

17

A synthetic biochemistry module for production of bio-based chemicals from glucose

Opgenorth, Paul H, Korman, Tyler P, Bowie, James U

Journal:

Nature Chemical Biology

Year:

2016

Language:

english

File:

PDF, 935 KB

english, 2016

18

Activation of innate and adaptive immunity as an effective combined strategy for cancer immunotherapy

Rakhmilevich, Alexander, Felder, Mildred, Lever, Lauren, Van De Voort, Tyler, Korman, Alan J, Gillies, Stephen D, Sondel, Paul M

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 248 KB

english, 2015

19

Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme

Sherkhanov, Saken, Korman, Tyler P., Clarke, Steven G, Bowie, James U.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 905 KB

english, 2016

20

Effective Combination of Innate and Adaptive Immunotherapeutic Approaches in a Mouse Melanoma Model

Rakhmilevich, Alexander L., Felder, Mildred, Lever, Lauren, Slowinski, Jacob, Rasmussen, Kayla, Hoefges, Anna, Van De Voort, Tyler J., Loibner, Hans, Korman, Alan J., Gillies, Stephen D., Sondel, Paul

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.63 MB

english, 2017

21

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway

Vinokur, Jeffrey M., Cummins, Matthew C., Korman, Tyler P., Bowie, James U.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

22

A synthetic biochemistry platform for cell free production of monoterpenes from glucose

Korman, Tyler P., Opgenorth, Paul H., Bowie, James U.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 861 KB

english, 2017

23

A molecular rheostat maintains ATP levels to drive a synthetic biochemistry system

Opgenorth, Paul H, Korman, Tyler P, Iancu, Liviu, Bowie, James U

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

24

Crystal Structure of Proteus mirabilis Lipase, a Novel Lipase from the Proteus/Psychrophilic Subfamily of Lipase Family I.1

Korman, Tyler P., Bowie, James U., Roujeinikova, Anna

Journal:

Year:

2012

Language:

english

File:

PDF, 607 KB

english, 2012

25

A cell-free platform for the prenylation of natural products and application to cannabinoid production

Valliere, Meaghan A., Korman, Tyler P., Woodall, Nicholas B., Khitrov, Gregory A., Taylor, Robert E., Baker, David, Bowie, James U.

Journal:

Nature Communications

Year:

2019

File:

PDF, 927 KB

2019

26

Synthetic Biochemistry: The Bio-inspired Cell-Free Approach to Commodity Chemical Production

Bowie, James U., Sherkhanov, Saken, Korman, Tyler P., Valliere, Meaghan A., Opgenorth, Paul H., Liu, Hongjiang

Journal:

Trends in Biotechnology

Year:

2020

Language:

english

File:

PDF, 1.68 MB

english, 2020

27

Isobutanol production freed from biological limits using synthetic biochemistry

Sherkhanov, Saken, Korman, Tyler P., Chan, Sum, Faham, Salem, Liu, Hongjiang, Sawaya, Michael R., Hsu, Wan-Ting, Vikram, Ellee, Cheng, Tiffany, Bowie, James U.

Journal:

Nature Communications

Year:

2020

File:

PDF, 1.59 MB

2020